| 2022-04-17 | HuescavZaragozaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-04-17 | TenerifevFuenlabradaLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2022-04-16 | Sp GijonvOviedoLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2022-04-16 | CartagenavAlcorconLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2022-04-16 | LeganesvMalagaLa Liga 2 · Spain | 0–3 | La Liga 2 · Spain |
| 2022-04-16 | ValladolidvAlmeriaLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2022-04-15 | EibarvLas PalmasLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2022-04-15 | AmorebietavMirandesLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-04-11 | AlmeriavPonferradinaLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2022-04-10 | MirandesvBurgosLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2022-04-10 | FuenlabradavHuescaLa Liga 2 · Spain | 2–3 | La Liga 2 · Spain |
| 2022-04-10 | IbizavEibarLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2022-04-10 | ZaragozavGironaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-04-10 | OviedovLeganesLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-04-09 | AlcorconvSp GijonLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-04-09 | Sociedad BvTenerifeLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2022-04-09 | MalagavValladolidLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2022-04-09 | Las PalmasvAmorebietaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-04-08 | LugovCartagenaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-04-04 | LeganesvFuenlabradaLa Liga 2 · Spain | 3–2 | La Liga 2 · Spain |
| 2022-04-03 | CartagenavOviedoLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2022-04-03 | HuescavAlmeriaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-04-03 | EibarvMirandesLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-04-03 | PonferradinavLas PalmasLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2022-04-03 | BurgosvSp GijonLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-04-02 | TenerifevZaragozaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-04-02 | AmorebietavIbizaLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2022-04-02 | ValladolidvLugoLa Liga 2 · Spain | 4–1 | La Liga 2 · Spain |
| 2022-04-02 | Sociedad BvAlcorconLa Liga 2 · Spain | 2–4 | La Liga 2 · Spain |
| 2022-04-01 | GironavMalagaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-03-28 | Las PalmasvLeganesLa Liga 2 · Spain | 4–2 | La Liga 2 · Spain |
| 2022-03-27 | AlcorconvValladolidLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2022-03-27 | MalagavHuescaLa Liga 2 · Spain | 0–2 | La Liga 2 · Spain |
| 2022-03-27 | AlmeriavGironaLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2022-03-27 | BurgosvTenerifeLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-03-27 | MirandesvPonferradinaLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2022-03-26 | IbizavSociedad BLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2022-03-26 | Sp GijonvCartagenaLa Liga 2 · Spain | 4–1 | La Liga 2 · Spain |
| 2022-03-26 | OviedovFuenlabradaLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2022-03-26 | EibarvLugoLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-03-25 | ZaragozavAmorebietaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-03-21 | TenerifevAlmeriaLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2022-03-20 | LeganesvSp GijonLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-03-20 | PonferradinavEibarLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2022-03-20 | AmorebietavAlcorconLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-03-19 | FuenlabradavMalagaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-03-19 | LugovOviedoLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-03-19 | ValladolidvLas PalmasLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2022-03-19 | Sociedad BvMirandesLa Liga 2 · Spain | 1–3 | La Liga 2 · Spain |
| 2022-03-19 | CartagenavZaragozaLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |