| 2021-12-21 | SevillavBarcelonaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2021-12-18 | SevillavAth MadridLa Liga · Spain | 2–1 | La Liga · Spain |
| 2021-12-11 | Ath BilbaovSevillaLa Liga · Spain | 0–1 | La Liga · Spain |
| 2021-12-04 | SevillavVillarrealLa Liga · Spain | 1–0 | La Liga · Spain |
| 2021-11-28 | Real MadridvSevillaLa Liga · Spain | 2–1 | La Liga · Spain |
| 2021-11-20 | SevillavAlavesLa Liga · Spain | 2–2 | La Liga · Spain |
| 2021-11-07 | BetisvSevillaLa Liga · Spain | 0–2 | La Liga · Spain |
| 2021-10-30 | SevillavOsasunaLa Liga · Spain | 2–0 | La Liga · Spain |
| 2021-10-27 | MallorcavSevillaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2021-10-24 | SevillavLevanteLa Liga · Spain | 5–3 | La Liga · Spain |
| 2021-10-17 | CeltavSevillaLa Liga · Spain | 0–1 | La Liga · Spain |
| 2021-10-03 | GranadavSevillaLa Liga · Spain | 1–0 | La Liga · Spain |
| 2021-09-25 | SevillavEspanolLa Liga · Spain | 2–0 | La Liga · Spain |
| 2021-09-22 | SevillavValenciaLa Liga · Spain | 3–1 | La Liga · Spain |
| 2021-09-19 | SociedadvSevillaLa Liga · Spain | 0–0 | La Liga · Spain |
| 2021-08-28 | ElchevSevillaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2021-08-23 | GetafevSevillaLa Liga · Spain | 0–1 | La Liga · Spain |
| 2021-08-15 | SevillavVallecanoLa Liga · Spain | 3–0 | La Liga · Spain |
| 2021-05-23 | SevillavAlavesLa Liga · Spain | 1–0 | La Liga · Spain |
| 2021-05-16 | VillarrealvSevillaLa Liga · Spain | 4–0 | La Liga · Spain |
| 2021-05-12 | SevillavValenciaLa Liga · Spain | 1–0 | La Liga · Spain |
| 2021-05-09 | Real MadridvSevillaLa Liga · Spain | 2–2 | La Liga · Spain |
| 2021-05-03 | SevillavAth BilbaoLa Liga · Spain | 0–1 | La Liga · Spain |
| 2021-04-25 | SevillavGranadaLa Liga · Spain | 2–1 | La Liga · Spain |
| 2021-04-21 | LevantevSevillaLa Liga · Spain | 0–1 | La Liga · Spain |
| 2021-04-18 | SociedadvSevillaLa Liga · Spain | 1–2 | La Liga · Spain |
| 2021-04-12 | CeltavSevillaLa Liga · Spain | 3–4 | La Liga · Spain |
| 2021-04-04 | SevillavAth MadridLa Liga · Spain | 1–0 | La Liga · Spain |
| 2021-03-20 | ValladolidvSevillaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2021-03-17 | SevillavElcheLa Liga · Spain | 2–0 | La Liga · Spain |
| 2021-03-14 | SevillavBetisLa Liga · Spain | 1–0 | La Liga · Spain |
| 2021-03-06 | ElchevSevillaLa Liga · Spain | 2–1 | La Liga · Spain |
| 2021-02-27 | SevillavBarcelonaLa Liga · Spain | 0–2 | La Liga · Spain |
| 2021-02-22 | OsasunavSevillaLa Liga · Spain | 0–2 | La Liga · Spain |
| 2021-02-13 | SevillavHuescaLa Liga · Spain | 1–0 | La Liga · Spain |
| 2021-02-06 | SevillavGetafeLa Liga · Spain | 3–0 | La Liga · Spain |
| 2021-01-30 | EibarvSevillaLa Liga · Spain | 0–2 | La Liga · Spain |
| 2021-01-23 | SevillavCadizLa Liga · Spain | 3–0 | La Liga · Spain |
| 2021-01-19 | AlavesvSevillaLa Liga · Spain | 1–2 | La Liga · Spain |
| 2021-01-12 | Ath MadridvSevillaLa Liga · Spain | 2–0 | La Liga · Spain |
| 2021-01-09 | SevillavSociedadLa Liga · Spain | 3–2 | La Liga · Spain |
| 2021-01-02 | BetisvSevillaLa Liga · Spain | 1–1 | La Liga · Spain |