| 2022-10-03 | Santos LagunavMazatlan FCLiga MX · Mexico | 3–0 | Liga MX · Mexico |
| 2022-09-24 | NecaxavMazatlan FCLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2022-09-17 | Mazatlan FCvTolucaLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-09-11 | Cruz AzulvMazatlan FCLiga MX · Mexico | 2–0 | Liga MX · Mexico |
| 2022-09-08 | Mazatlan FCvAtlasLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2022-09-04 | MonterreyvMazatlan FCLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2022-08-27 | Mazatlan FCvClub AmericaLiga MX · Mexico | 1–3 | Liga MX · Mexico |
| 2022-08-21 | JuarezvMazatlan FCLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-08-17 | Mazatlan FCvQueretaroLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-08-13 | Club LeonvMazatlan FCLiga MX · Mexico | 0–3 | Liga MX · Mexico |
| 2022-08-06 | Mazatlan FCvGuadalajara ChivasLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2022-07-31 | Club TijuanavMazatlan FCLiga MX · Mexico | 2–0 | Liga MX · Mexico |
| 2022-07-28 | UNAM PumasvMazatlan FCLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-07-23 | Mazatlan FCvAtl. San LuisLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-07-19 | PachucavMazatlan FCLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-07-09 | Mazatlan FCvTigres UANLLiga MX · Mexico | 0–1 | Liga MX · Mexico |
| 2022-07-02 | Mazatlan FCvPueblaLiga MX · Mexico | 2–4 | Liga MX · Mexico |
| 2022-05-08 | PueblavMazatlan FCLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2022-04-30 | Mazatlan FCvPueblaLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2022-04-23 | JuarezvMazatlan FCLiga MX · Mexico | 0–2 | Liga MX · Mexico |
| 2022-04-20 | Mazatlan FCvSantos LagunaLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2022-04-15 | AtlasvMazatlan FCLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2022-04-09 | Mazatlan FCvCruz AzulLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-04-02 | Atl. San LuisvMazatlan FCLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2022-03-26 | UNAM PumasvMazatlan FCLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-03-21 | Mazatlan FCvClub LeonLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2022-03-12 | MonterreyvMazatlan FCLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2022-03-02 | Mazatlan FCvNecaxaLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2022-02-25 | PachucavMazatlan FCLiga MX · Mexico | 3–1 | Liga MX · Mexico |
| 2022-02-19 | QueretarovMazatlan FCLiga MX · Mexico | 2–0 | Liga MX · Mexico |
| 2022-02-17 | Mazatlan FCvClub AmericaLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2022-02-12 | Mazatlan FCvClub TijuanaLiga MX · Mexico | 2–0 | Liga MX · Mexico |
| 2022-02-07 | Tigres UANLvMazatlan FCLiga MX · Mexico | 4–3 | Liga MX · Mexico |
| 2022-01-22 | Mazatlan FCvTolucaLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2022-01-10 | Guadalajara ChivasvMazatlan FCLiga MX · Mexico | 3–0 | Liga MX · Mexico |