| 2021-11-21 | PueblavGuadalajara ChivasLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2021-11-06 | Mazatlan FCvGuadalajara ChivasLiga MX · Mexico | 0–1 | Liga MX · Mexico |
| 2021-10-31 | Tigres UANLvGuadalajara ChivasLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2021-10-24 | Guadalajara ChivasvCruz AzulLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2021-10-21 | Club TijuanavGuadalajara ChivasLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2021-10-17 | Guadalajara ChivasvTolucaLiga MX · Mexico | 2–0 | Liga MX · Mexico |
| 2021-10-03 | Guadalajara ChivasvAtlasLiga MX · Mexico | 0–1 | Liga MX · Mexico |
| 2021-09-30 | QueretarovGuadalajara ChivasLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2021-09-26 | Club AmericavGuadalajara ChivasLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2021-09-19 | Guadalajara ChivasvPachucaLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2021-09-12 | UNAM PumasvGuadalajara ChivasLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2021-08-28 | Guadalajara ChivasvNecaxaLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2021-08-22 | MonterreyvGuadalajara ChivasLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2021-08-19 | Guadalajara ChivasvClub LeonLiga MX · Mexico | 0–3 | Liga MX · Mexico |
| 2021-08-16 | Santos LagunavGuadalajara ChivasLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2021-08-07 | Guadalajara ChivasvJuarezLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2021-07-31 | PueblavGuadalajara ChivasLiga MX · Mexico | 0–2 | Liga MX · Mexico |
| 2021-07-25 | Guadalajara ChivasvAtl. San LuisLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2021-05-10 | PachucavGuadalajara ChivasLiga MX · Mexico | 4–2 | Liga MX · Mexico |
| 2021-05-01 | Guadalajara ChivasvTigres UANLLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2021-04-25 | AtlasvGuadalajara ChivasLiga MX · Mexico | 0–1 | Liga MX · Mexico |
| 2021-04-22 | MonterreyvGuadalajara ChivasLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2021-04-18 | Guadalajara ChivasvClub TijuanaLiga MX · Mexico | 2–0 | Liga MX · Mexico |
| 2021-04-11 | Cruz AzulvGuadalajara ChivasLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2021-04-04 | Guadalajara ChivasvSantos LagunaLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2021-03-15 | Guadalajara ChivasvClub AmericaLiga MX · Mexico | 0–3 | Liga MX · Mexico |
| 2021-03-07 | Mazatlan FCvGuadalajara ChivasLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2021-03-04 | QueretarovGuadalajara ChivasLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2021-03-01 | Guadalajara ChivasvUNAM PumasLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2021-02-23 | PachucavGuadalajara ChivasLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2021-02-14 | Guadalajara ChivasvNecaxaLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2021-02-09 | Club LeonvGuadalajara ChivasLiga MX · Mexico | 1–3 | Liga MX · Mexico |
| 2021-01-31 | Guadalajara ChivasvJuarezLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2021-01-22 | Atl. San LuisvGuadalajara ChivasLiga MX · Mexico | 3–1 | Liga MX · Mexico |
| 2021-01-16 | Guadalajara ChivasvTolucaLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2021-01-09 | PueblavGuadalajara ChivasLiga MX · Mexico | 1–1 | Liga MX · Mexico |