| 2010-12-12 | BresciavSampdoriaSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-12-05 | SampdoriavBariSerie A · Italy | 3–0 | Serie A · Italy |
| 2010-11-27 | SampdoriavMilanSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-11-21 | LeccevSampdoriaSerie A · Italy | 2–3 | Serie A · Italy |
| 2010-11-14 | SampdoriavChievoSerie A · Italy | 0–0 | Serie A · Italy |
| 2010-11-11 | ParmavSampdoriaSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-11-07 | SampdoriavCataniaSerie A · Italy | 0–0 | Serie A · Italy |
| 2010-10-31 | CesenavSampdoriaSerie A · Italy | 0–1 | Serie A · Italy |
| 2010-10-24 | IntervSampdoriaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-10-17 | SampdoriavFiorentinaSerie A · Italy | 2–1 | Serie A · Italy |
| 2010-10-03 | BolognavSampdoriaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-09-26 | SampdoriavUdineseSerie A · Italy | 0–0 | Serie A · Italy |
| 2010-09-22 | CagliarivSampdoriaSerie A · Italy | 0–0 | Serie A · Italy |
| 2010-09-19 | SampdoriavNapoliSerie A · Italy | 1–2 | Serie A · Italy |
| 2010-09-12 | JuventusvSampdoriaSerie A · Italy | 3–3 | Serie A · Italy |
| 2010-08-29 | SampdoriavLazioSerie A · Italy | 2–0 | Serie A · Italy |
| 2010-05-16 | SampdoriavNapoliSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-05-09 | PalermovSampdoriaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-05-02 | SampdoriavLivornoSerie A · Italy | 2–0 | Serie A · Italy |
| 2010-04-25 | RomavSampdoriaSerie A · Italy | 1–2 | Serie A · Italy |
| 2010-04-18 | SampdoriavMilanSerie A · Italy | 2–1 | Serie A · Italy |
| 2010-04-11 | SampdoriavGenoaSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-04-03 | ChievovSampdoriaSerie A · Italy | 1–2 | Serie A · Italy |
| 2010-03-28 | SampdoriavCagliariSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-03-24 | BarivSampdoriaSerie A · Italy | 2–1 | Serie A · Italy |
| 2010-03-21 | SampdoriavJuventusSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-03-14 | BolognavSampdoriaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-03-07 | SampdoriavLazioSerie A · Italy | 2–1 | Serie A · Italy |
| 2010-02-28 | ParmavSampdoriaSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-02-20 | IntervSampdoriaSerie A · Italy | 0–0 | Serie A · Italy |
| 2010-02-13 | SampdoriavFiorentinaSerie A · Italy | 2–0 | Serie A · Italy |
| 2010-02-07 | SienavSampdoriaSerie A · Italy | 1–2 | Serie A · Italy |
| 2010-01-31 | SampdoriavAtalantaSerie A · Italy | 2–0 | Serie A · Italy |
| 2010-01-24 | UdinesevSampdoriaSerie A · Italy | 2–3 | Serie A · Italy |
| 2010-01-17 | SampdoriavCataniaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-01-10 | NapolivSampdoriaSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-01-06 | SampdoriavPalermoSerie A · Italy | 1–1 | Serie A · Italy |