| 2022-12-28 | TroyesvNantesLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-11-13 | NantesvAjaccioLigue 1 · France | 2–2 | Ligue 1 · France |
| 2022-11-06 | ReimsvNantesLigue 1 · France | 1–0 | Ligue 1 · France |
| 2022-10-30 | NantesvClermontLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-10-23 | NicevNantesLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-10-16 | NantesvBrestLigue 1 · France | 4–1 | Ligue 1 · France |
| 2022-10-09 | RennesvNantesLigue 1 · France | 3–0 | Ligue 1 · France |
| 2022-10-02 |  MonacovNantesLigue 1 · France | 4–1 | Ligue 1 · France |
| 2022-09-18 | NantesvLensLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-09-11 | LorientvNantesLigue 1 · France | 3–2 | Ligue 1 · France |
| 2022-09-03 | NantesvParis SGLigue 1 · France | 0–3 | Ligue 1 · France |
| 2022-08-31 | StrasbourgvNantesLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-08-28 | NantesvToulouseLigue 1 · France | 3–1 | Ligue 1 · France |
| 2022-08-20 | MarseillevNantesLigue 1 · France | 2–1 | Ligue 1 · France |
| 2022-08-12 | NantesvLilleLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-08-07 | AngersvNantesLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-05-21 | NantesvSt EtienneLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-05-14 | LyonvNantesLigue 1 · France | 3–2 | Ligue 1 · France |
| 2022-05-11 | NantesvRennesLigue 1 · France | 2–1 | Ligue 1 · France |
| 2022-04-30 | LensvNantesLigue 1 · France | 2–2 | Ligue 1 · France |
| 2022-04-24 | NantesvBordeauxLigue 1 · France | 5–3 | Ligue 1 · France |
| 2022-04-20 | MarseillevNantesLigue 1 · France | 3–2 | Ligue 1 · France |
| 2022-04-17 | NantesvAngersLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-04-10 | BrestvNantesLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-04-03 | ClermontvNantesLigue 1 · France | 2–3 | Ligue 1 · France |
| 2022-03-19 | NantesvLilleLigue 1 · France | 0–1 | Ligue 1 · France |
| 2022-03-12 | TroyesvNantesLigue 1 · France | 1–0 | Ligue 1 · France |
| 2022-03-06 | NantesvMontpellierLigue 1 · France | 2–0 | Ligue 1 · France |
| 2022-02-27 | MetzvNantesLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-02-19 | NantesvParis SGLigue 1 · France | 3–1 | Ligue 1 · France |
| 2022-02-13 | NantesvReimsLigue 1 · France | 1–0 | Ligue 1 · France |
| 2022-02-06 | StrasbourgvNantesLigue 1 · France | 1–0 | Ligue 1 · France |
| 2022-01-23 | NantesvLorientLigue 1 · France | 4–2 | Ligue 1 · France |
| 2022-01-14 | NicevNantesLigue 1 · France | 2–1 | Ligue 1 · France |
| 2022-01-09 | NantesvMonacoLigue 1 · France | 0–0 | Ligue 1 · France |