| 2022-09-07 | LorientvLyonLigue 1 · France | 3–1 | Ligue 1 · France |
| 2022-09-04 | AjacciovLorientLigue 1 · France | 0–1 | Ligue 1 · France |
| 2022-08-31 | LensvLorientLigue 1 · France | 5–2 | Ligue 1 · France |
| 2022-08-28 | LorientvClermontLigue 1 · France | 2–1 | Ligue 1 · France |
| 2022-08-21 | ToulousevLorientLigue 1 · France | 2–2 | Ligue 1 · France |
| 2022-08-07 | RennesvLorientLigue 1 · France | 0–1 | Ligue 1 · France |
| 2022-05-21 | LorientvTroyesLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-05-14 | BordeauxvLorientLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-05-08 | LorientvMarseilleLigue 1 · France | 0–3 | Ligue 1 · France |
| 2022-05-01 | LorientvReimsLigue 1 · France | 1–2 | Ligue 1 · France |
| 2022-04-24 | RennesvLorientLigue 1 · France | 5–0 | Ligue 1 · France |
| 2022-04-20 | LorientvMetzLigue 1 · France | 1–0 | Ligue 1 · France |
| 2022-04-17 | NicevLorientLigue 1 · France | 2–1 | Ligue 1 · France |
| 2022-04-08 | LorientvSt EtienneLigue 1 · France | 6–2 | Ligue 1 · France |
| 2022-04-03 | Paris SGvLorientLigue 1 · France | 5–1 | Ligue 1 · France |
| 2022-03-20 | LorientvStrasbourgLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-03-13 | ClermontvLorientLigue 1 · France | 0–2 | Ligue 1 · France |
| 2022-03-04 | LorientvLyonLigue 1 · France | 1–4 | Ligue 1 · France |
| 2022-02-27 | BrestvLorientLigue 1 · France | 0–1 | Ligue 1 · France |
| 2022-02-20 | LorientvMontpellierLigue 1 · France | 0–1 | Ligue 1 · France |
| 2022-02-13 |  MonacovLorientLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-02-06 | LorientvLensLigue 1 · France | 2–0 | Ligue 1 · France |
| 2022-01-23 | NantesvLorientLigue 1 · France | 4–2 | Ligue 1 · France |
| 2022-01-19 | LillevLorientLigue 1 · France | 3–1 | Ligue 1 · France |
| 2022-01-16 | LorientvAngersLigue 1 · France | 0–0 | Ligue 1 · France |
| 2021-12-22 | LorientvParis SGLigue 1 · France | 1–1 | Ligue 1 · France |
| 2021-12-12 | MetzvLorientLigue 1 · France | 4–1 | Ligue 1 · France |
| 2021-12-05 | LorientvNantesLigue 1 · France | 0–1 | Ligue 1 · France |
| 2021-12-01 | TroyesvLorientLigue 1 · France | 2–0 | Ligue 1 · France |
| 2021-11-28 | LorientvRennesLigue 1 · France | 0–2 | Ligue 1 · France |
| 2021-11-21 | AngersvLorientLigue 1 · France | 1–0 | Ligue 1 · France |
| 2021-11-07 | LorientvBrestLigue 1 · France | 1–2 | Ligue 1 · France |
| 2021-10-31 | StrasbourgvLorientLigue 1 · France | 4–0 | Ligue 1 · France |
| 2021-10-24 | LorientvBordeauxLigue 1 · France | 1–1 | Ligue 1 · France |
| 2021-10-17 | MarseillevLorientLigue 1 · France | 4–1 | Ligue 1 · France |
| 2021-10-03 | LorientvClermontLigue 1 · France | 1–1 | Ligue 1 · France |
| 2021-09-25 | LyonvLorientLigue 1 · France | 1–1 | Ligue 1 · France |
| 2021-09-22 | LorientvNiceLigue 1 · France | 1–0 | Ligue 1 · France |
| 2021-09-19 | ReimsvLorientLigue 1 · France | 0–0 | Ligue 1 · France |
| 2021-09-10 | LorientvLilleLigue 1 · France | 2–1 | Ligue 1 · France |
| 2021-08-29 | LensvLorientLigue 1 · France | 2–2 | Ligue 1 · France |
| 2021-08-22 | MontpelliervLorientLigue 1 · France | 3–1 | Ligue 1 · France |
| 2021-08-13 | LorientvMonacoLigue 1 · France | 1–0 | Ligue 1 · France |
| 2021-08-08 | St EtiennevLorientLigue 1 · France | 1–1 | Ligue 1 · France |
| 2021-05-23 | StrasbourgvLorientLigue 1 · France | 1–1 | Ligue 1 · France |
| 2021-05-16 | LorientvMetzLigue 1 · France | 2–1 | Ligue 1 · France |
| 2021-05-08 | LyonvLorientLigue 1 · France | 4–1 | Ligue 1 · France |
| 2021-05-02 | LorientvAngersLigue 1 · France | 2–0 | Ligue 1 · France |
| 2021-04-25 | LorientvBordeauxLigue 1 · France | 4–1 | Ligue 1 · France |
| 2021-04-17 | MarseillevLorientLigue 1 · France | 3–2 | Ligue 1 · France |