| 2017-04-29 | SouthportvLincolnNational League · England | 1–1 | National League · England |
| 2017-04-22 | TranmerevSouthportNational League · England | 4–1 | National League · England |
| 2017-04-17 | SouthportvForest GreenNational League · England | 2–0 | National League · England |
| 2017-04-14 | Dover AthleticvSouthportNational League · England | 3–0 | National League · England |
| 2017-04-08 | SuttonvSouthportNational League · England | 2–2 | National League · England |
| 2017-04-04 | SouthportvMacclesfieldNational League · England | 1–2 | National League · England |
| 2017-04-01 | SouthportvGuiseleyNational League · England | 0–1 | National League · England |
| 2017-03-25 | SouthportvBoreham WoodNational League · England | 1–0 | National League · England |
| 2017-03-21 | YorkvSouthportNational League · England | 5–3 | National League · England |
| 2017-03-18 | Braintree TownvSouthportNational League · England | 2–0 | National League · England |
| 2017-03-11 | SouthportvTorquayNational League · England | 1–2 | National League · England |
| 2017-03-04 | MaidstonevSouthportNational League · England | 4–2 | National League · England |
| 2017-02-25 | SouthportvChesterNational League · England | 0–1 | National League · England |
| 2017-02-18 | WokingvSouthportNational League · England | 0–0 | National League · England |
| 2017-02-11 | SouthportvDag and RedNational League · England | 1–4 | National League · England |
| 2017-02-04 | GatesheadvSouthportNational League · England | 3–0 | National League · England |
| 2017-01-28 | BromleyvSouthportNational League · England | 3–1 | National League · England |
| 2017-01-21 | SouthportvNorth FerribyNational League · England | 2–4 | National League · England |
| 2017-01-10 | BarrowvSouthportNational League · England | 0–1 | National League · England |
| 2017-01-07 | AldershotvSouthportNational League · England | 2–1 | National League · England |
| 2017-01-01 | SouthportvWrexhamNational League · England | 3–2 | National League · England |
| 2016-12-26 | WrexhamvSouthportNational League · England | 1–0 | National League · England |
| 2016-12-17 | SouthportvEastleighNational League · England | 4–3 | National League · England |
| 2016-11-29 | SouthportvSolihullNational League · England | 0–0 | National League · England |
| 2016-11-26 | SouthportvBraintree TownNational League · England | 4–5 | National League · England |
| 2016-11-22 | ChestervSouthportNational League · England | 2–2 | National League · England |
| 2016-11-19 | Boreham WoodvSouthportNational League · England | 2–0 | National League · England |
| 2016-11-12 | SouthportvMaidstoneNational League · England | 3–2 | National League · England |
| 2016-10-29 | TorquayvSouthportNational League · England | 1–2 | National League · England |
| 2016-10-25 | SouthportvYorkNational League · England | 2–0 | National League · England |
| 2016-10-22 | SouthportvSuttonNational League · England | 1–1 | National League · England |
| 2016-10-08 | GuiseleyvSouthportNational League · England | 2–1 | National League · England |
| 2016-10-04 | SolihullvSouthportNational League · England | 4–0 | National League · England |
| 2016-10-01 | SouthportvBromleyNational League · England | 1–2 | National League · England |
| 2016-09-24 | North FerribyvSouthportNational League · England | 0–1 | National League · England |
| 2016-09-17 | SouthportvAldershotNational League · England | 1–1 | National League · England |
| 2016-09-13 | SouthportvBarrowNational League · England | 1–4 | National League · England |
| 2016-09-10 | EastleighvSouthportNational League · England | 1–1 | National League · England |
| 2016-09-03 | SouthportvDover AthleticNational League · England | 0–1 | National League · England |
| 2016-08-29 | Forest GreenvSouthportNational League · England | 5–1 | National League · England |
| 2016-08-27 | SouthportvTranmereNational League · England | 1–1 | National League · England |
| 2016-08-20 | LincolnvSouthportNational League · England | 4–0 | National League · England |
| 2016-08-16 | MacclesfieldvSouthportNational League · England | 3–1 | National League · England |
| 2016-08-13 | SouthportvWokingNational League · England | 2–1 | National League · England |
| 2016-08-09 | SouthportvGatesheadNational League · England | 0–3 | National League · England |
| 2016-08-06 | Dag and RedvSouthportNational League · England | 3–0 | National League · England |
| 2016-04-30 | SouthportvKidderminsterNational League · England | 3–4 | National League · England |
| 2016-04-23 | AldershotvSouthportNational League · England | 1–2 | National League · England |
| 2016-04-16 | SouthportvLincolnNational League · England | 2–2 | National League · England |
| 2016-04-09 | Boreham WoodvSouthportNational League · England | 0–2 | National League · England |