| 2022-12-26 | SouthendvBromleyNational League · England | 0–1 | National League · England |
| 2022-12-03 | SouthendvAltrinchamNational League · England | 2–2 | National League · England |
| 2022-11-26 | AldershotvSouthendNational League · England | 2–0 | National League · England |
| 2022-11-19 | GatesheadvSouthendNational League · England | 3–1 | National League · England |
| 2022-11-12 | SouthendvDorkingNational League · England | 2–0 | National League · England |
| 2022-11-08 | SouthendvNotts CountyNational League · England | 2–2 | National League · England |
| 2022-11-01 | BarnetvSouthendNational League · England | 0–3 | National League · England |
| 2022-10-29 | YorkvSouthendNational League · England | 0–2 | National League · England |
| 2022-10-25 | MaidstonevSouthendNational League · England | 0–3 | National League · England |
| 2022-10-22 | SouthendvScunthorpeNational League · England | 3–0 | National League · England |
| 2022-10-08 | Dag and RedvSouthendNational League · England | 1–1 | National League · England |
| 2022-10-04 | SouthendvWokingNational League · England | 1–1 | National League · England |
| 2022-10-01 | SouthendvYeovilNational League · England | 1–0 | National League · England |
| 2022-09-24 | WealdstonevSouthendNational League · England | 0–1 | National League · England |
| 2022-09-17 | SouthendvWrexhamNational League · England | 0–0 | National League · England |
| 2022-09-13 | ChesterfieldvSouthendNational League · England | 3–2 | National League · England |
| 2022-09-03 | SouthendvTorquayNational League · England | 1–2 | National League · England |
| 2022-08-29 | SouthendvMaidenheadNational League · England | 2–0 | National League · England |
| 2022-08-27 | EastleighvSouthendNational League · England | 2–1 | National League · England |
| 2022-08-20 | SouthendvOldhamNational League · England | 1–0 | National League · England |
| 2022-08-16 | HalifaxvSouthendNational League · England | 0–0 | National League · England |
| 2022-08-13 | SolihullvSouthendNational League · England | 1–1 | National League · England |
| 2022-08-06 | SouthendvBoreham WoodNational League · England | 0–1 | National League · England |
| 2022-05-15 | SouthendvTorquayNational League · England | 1–1 | National League · England |
| 2022-05-02 | SouthendvWeymouthNational League · England | 1–1 | National League · England |
| 2022-04-30 | WrexhamvSouthendNational League · England | 1–0 | National League · England |
| 2022-04-26 | SouthendvBoreham WoodNational League · England | 1–0 | National League · England |
| 2022-04-23 | SouthendvHalifaxNational League · England | 1–0 | National League · England |
| 2022-04-18 | BarnetvSouthendNational League · England | 1–3 | National League · England |
| 2022-04-15 | SouthendvWealdstoneNational League · England | 0–1 | National League · England |
| 2022-04-09 | StockportvSouthendNational League · England | 5–0 | National League · England |
| 2022-04-02 | SouthendvNotts CountyNational League · England | 0–3 | National League · England |
| 2022-03-26 | YeovilvSouthendNational League · England | 2–0 | National League · England |
| 2022-03-22 | MaidenheadvSouthendNational League · England | 2–1 | National League · England |
| 2022-03-19 | SouthendvAltrinchamNational League · England | 2–0 | National League · England |
| 2022-03-15 | SouthendvDag and RedNational League · England | 0–3 | National League · England |
| 2022-03-08 | SouthendvGrimsbyNational League · England | 1–0 | National League · England |
| 2022-03-05 | ChesterfieldvSouthendNational League · England | 2–2 | National League · England |
| 2022-02-26 | SouthendvSolihullNational League · England | 1–1 | National League · England |
| 2022-02-22 | EastleighvSouthendNational League · England | 1–1 | National League · England |
| 2022-02-12 | WokingvSouthendNational League · England | 2–3 | National League · England |
| 2022-02-08 | SouthendvBromleyNational League · England | 2–0 | National League · England |
| 2022-02-01 | SouthendvBarnetNational League · England | 2–1 | National League · England |
| 2022-01-29 | Dover AthleticvSouthendNational League · England | 0–1 | National League · England |
| 2022-01-25 | AldershotvSouthendNational League · England | 1–1 | National League · England |
| 2022-01-21 | SouthendvKings LynnNational League · England | 2–1 | National League · England |
| 2022-01-11 | SouthendvYeovilNational League · England | 2–1 | National League · England |
| 2022-01-08 | WeymouthvSouthendNational League · England | 0–1 | National League · England |