| 2016-04-02 | SouthportvWokingNational League · England | 2–2 | National League · England |
| 2016-03-28 | AltrinchamvSouthportNational League · England | 1–1 | National League · England |
| 2016-03-26 | SouthportvGuiseleyNational League · England | 2–0 | National League · England |
| 2016-03-19 | TorquayvSouthportNational League · England | 1–0 | National League · England |
| 2016-03-12 | SouthportvWelling UnitedNational League · England | 3–3 | National League · England |
| 2016-03-08 | GrimsbyvSouthportNational League · England | 1–0 | National League · England |
| 2016-03-05 | SouthportvHalifaxNational League · England | 0–1 | National League · England |
| 2016-03-01 | Dover AthleticvSouthportNational League · England | 1–2 | National League · England |
| 2016-02-27 | SouthportvBoreham WoodNational League · England | 0–3 | National League · England |
| 2016-02-20 | LincolnvSouthportNational League · England | 3–1 | National League · England |
| 2016-02-13 | SouthportvBraintree TownNational League · England | 1–1 | National League · England |
| 2016-02-06 | TranmerevSouthportNational League · England | 1–0 | National League · England |
| 2016-01-26 | SouthportvForest GreenNational League · England | 0–1 | National League · England |
| 2016-01-23 | ChestervSouthportNational League · England | 0–0 | National League · England |
| 2016-01-09 | BromleyvSouthportNational League · England | 0–0 | National League · England |
| 2016-01-02 | SouthportvWrexhamNational League · England | 3–2 | National League · England |
| 2015-12-28 | SouthportvBarrowNational League · England | 2–1 | National League · England |
| 2015-12-26 | WrexhamvSouthportNational League · England | 0–1 | National League · England |
| 2015-12-19 | SouthportvBromleyNational League · England | 5–3 | National League · England |
| 2015-12-08 | GatesheadvSouthportNational League · England | 0–1 | National League · England |
| 2015-12-05 | SouthportvMacclesfieldNational League · England | 3–1 | National League · England |
| 2015-11-28 | EastleighvSouthportNational League · England | 1–0 | National League · England |
| 2015-11-21 | Welling UnitedvSouthportNational League · England | 0–1 | National League · England |
| 2015-11-14 | SouthportvCheltenhamNational League · England | 0–4 | National League · England |
| 2015-10-31 | SouthportvAldershotNational League · England | 1–1 | National League · England |
| 2015-10-17 | KidderminstervSouthportNational League · England | 0–1 | National League · England |
| 2015-10-13 | SouthportvChesterNational League · England | 1–2 | National League · England |
| 2015-10-10 | SouthportvTorquayNational League · England | 0–1 | National League · England |
| 2015-10-03 | WokingvSouthportNational League · England | 1–2 | National League · England |
| 2015-09-26 | SouthportvGrimsbyNational League · England | 0–4 | National League · England |
| 2015-09-22 | GuiseleyvSouthportNational League · England | 1–1 | National League · England |
| 2015-09-19 | HalifaxvSouthportNational League · England | 2–2 | National League · England |
| 2015-09-15 | SouthportvTranmereNational League · England | 2–2 | National League · England |
| 2015-09-12 | Forest GreenvSouthportNational League · England | 2–1 | National League · England |
| 2015-09-05 | SouthportvDover AthleticNational League · England | 0–0 | National League · England |
| 2015-08-31 | SouthportvAltrinchamNational League · England | 3–0 | National League · England |
| 2015-08-29 | BarrowvSouthportNational League · England | 1–0 | National League · England |
| 2015-08-22 | Braintree TownvSouthportNational League · England | 1–0 | National League · England |
| 2015-08-18 | SouthportvGatesheadNational League · England | 1–2 | National League · England |
| 2015-08-15 | CheltenhamvSouthportNational League · England | 3–0 | National League · England |
| 2015-08-11 | MacclesfieldvSouthportNational League · England | 0–0 | National League · England |
| 2015-08-08 | SouthportvEastleighNational League · England | 0–4 | National League · England |
| 2015-04-25 | Welling UnitedvSouthportNational League · England | 0–1 | National League · England |
| 2015-04-18 | SouthportvGrimsbyNational League · England | 2–2 | National League · England |
| 2015-04-14 | SouthportvBraintree TownNational League · England | 0–2 | National League · England |
| 2015-04-11 | Bristol RvsvSouthportNational League · England | 2–0 | National League · England |
| 2015-04-06 | SouthportvTelford UnitedNational League · England | 0–3 | National League · England |
| 2015-04-03 | AltrinchamvSouthportNational League · England | 2–0 | National League · England |
| 2015-03-28 | SouthportvTorquayNational League · England | 2–1 | National League · England |
| 2015-03-21 | SouthportvDartfordNational League · England | 2–0 | National League · England |