| 2022-12-29 | BarrowvTranmereLeague Two · England | 1–2 | League Two · England |
| 2022-12-26 | TranmerevDoncasterLeague Two · England | 3–0 | League Two · England |
| 2022-12-10 | GrimsbyvTranmereLeague Two · England | 2–1 | League Two · England |
| 2022-12-03 | NorthamptonvTranmereLeague Two · England | 0–0 | League Two · England |
| 2022-11-19 | TranmerevAFC WimbledonLeague Two · England | 0–2 | League Two · England |
| 2022-11-12 | SwindonvTranmereLeague Two · England | 1–1 | League Two · England |
| 2022-11-01 | TranmerevStockportLeague Two · England | 0–0 | League Two · England |
| 2022-10-29 | TranmerevCarlisleLeague Two · England | 0–2 | League Two · England |
| 2022-10-25 | TranmerevRochdaleLeague Two · England | 1–1 | League Two · England |
| 2022-10-22 | HarrogatevTranmereLeague Two · England | 1–1 | League Two · England |
| 2022-10-14 | TranmerevCreweLeague Two · England | 3–0 | League Two · England |
| 2022-10-08 | SuttonvTranmereLeague Two · England | 0–2 | League Two · England |
| 2022-10-01 | TranmerevBarrowLeague Two · England | 1–0 | League Two · England |
| 2022-09-24 | WalsallvTranmereLeague Two · England | 0–1 | League Two · England |
| 2022-09-17 | SalfordvTranmereLeague Two · England | 0–1 | League Two · England |
| 2022-09-13 | TranmerevBradfordLeague Two · England | 1–2 | League Two · England |
| 2022-09-03 | Leyton OrientvTranmereLeague Two · England | 2–0 | League Two · England |
| 2022-08-27 | TranmerevColchesterLeague Two · England | 2–0 | League Two · England |
| 2022-08-20 | Newport CountyvTranmereLeague Two · England | 2–1 | League Two · England |
| 2022-08-16 | HartlepoolvTranmereLeague Two · England | 0–0 | League Two · England |
| 2022-08-13 | TranmerevGillinghamLeague Two · England | 3–0 | League Two · England |
| 2022-08-06 | MansfieldvTranmereLeague Two · England | 1–0 | League Two · England |
| 2022-07-30 | TranmerevStevenageLeague Two · England | 1–2 | League Two · England |
| 2022-05-07 | Leyton OrientvTranmereLeague Two · England | 0–1 | League Two · England |
| 2022-04-30 | TranmerevOldhamLeague Two · England | 2–0 | League Two · England |
| 2022-04-23 | StevenagevTranmereLeague Two · England | 2–0 | League Two · England |
| 2022-04-18 | TranmerevExeterLeague Two · England | 2–0 | League Two · England |
| 2022-04-15 | BradfordvTranmereLeague Two · England | 1–1 | League Two · England |
| 2022-04-09 | TranmerevBristol RvsLeague Two · England | 1–1 | League Two · England |
| 2022-04-02 | TranmerevCarlisleLeague Two · England | 2–2 | League Two · England |
| 2022-03-26 | ColchestervTranmereLeague Two · England | 1–0 | League Two · England |
| 2022-03-19 | SuttonvTranmereLeague Two · England | 1–1 | League Two · England |
| 2022-03-15 | TranmerevHarrogateLeague Two · England | 2–0 | League Two · England |
| 2022-03-11 | TranmerevMansfieldLeague Two · England | 3–2 | League Two · England |
| 2022-03-05 | NorthamptonvTranmereLeague Two · England | 3–2 | League Two · England |
| 2022-02-26 | Newport CountyvTranmereLeague Two · England | 4–2 | League Two · England |
| 2022-02-19 | TranmerevPort ValeLeague Two · England | 1–1 | League Two · England |
| 2022-02-15 | HartlepoolvTranmereLeague Two · England | 1–0 | League Two · England |
| 2022-02-12 | WalsallvTranmereLeague Two · England | 1–0 | League Two · England |
| 2022-02-08 | TranmerevSwindonLeague Two · England | 3–0 | League Two · England |
| 2022-02-05 | BarrowvTranmereLeague Two · England | 1–1 | League Two · England |
| 2022-02-01 | TranmerevStevenageLeague Two · England | 1–0 | League Two · England |
| 2022-01-29 | TranmerevForest GreenLeague Two · England | 0–4 | League Two · England |
| 2022-01-22 | Crawley TownvTranmereLeague Two · England | 0–1 | League Two · England |
| 2022-01-15 | TranmerevRochdaleLeague Two · England | 2–0 | League Two · England |
| 2022-01-11 | SalfordvTranmereLeague Two · England | 1–1 | League Two · England |
| 2022-01-08 | TranmerevScunthorpeLeague Two · England | 4–0 | League Two · England |