| 2025-12-29 | GillinghamvColchesterLeague Two · England | 1–1 | League Two · England |
| 2025-12-26 | Crawley TownvColchesterLeague Two · England | 1–1 | League Two · England |
| 2025-12-20 | ColchestervNewport CountyLeague Two · England | 4–1 | League Two · England |
| 2025-12-13 | SalfordvColchesterLeague Two · England | 4–3 | League Two · England |
| 2025-12-06 | ColchestervGillinghamLeague Two · England | 0–0 | League Two · England |
| 2025-11-29 | ColchestervCheltenhamLeague Two · England | 2–0 | League Two · England |
| 2025-11-22 | Notts CountyvColchesterLeague Two · England | 1–3 | League Two · England |
| 2025-11-15 | WalsallvColchesterLeague Two · England | 0–2 | League Two · England |
| 2025-11-08 | ColchestervBromleyLeague Two · England | 0–2 | League Two · England |
| 2025-10-25 | SwindonvColchesterLeague Two · England | 0–0 | League Two · England |
| 2025-10-18 | ColchestervHarrogateLeague Two · England | 3–1 | League Two · England |
| 2025-10-11 | GrimsbyvColchesterLeague Two · England | 1–2 | League Two · England |
| 2025-10-04 | ColchestervChesterfieldLeague Two · England | 6–2 | League Two · England |
| 2025-09-27 | Fleetwood TownvColchesterLeague Two · England | 4–2 | League Two · England |
| 2025-09-20 | ColchestervBristol RvsLeague Two · England | 1–1 | League Two · England |
| 2025-09-13 | AccringtonvColchesterLeague Two · England | 1–0 | League Two · England |
| 2025-09-06 | ColchestervCreweLeague Two · England | 1–1 | League Two · England |
| 2025-08-30 | BarnetvColchesterLeague Two · England | 1–1 | League Two · England |
| 2025-08-23 | ColchestervBarrowLeague Two · England | 0–2 | League Two · England |
| 2025-08-19 | ColchestervCambridgeLeague Two · England | 1–2 | League Two · England |
| 2025-08-16 | ShrewsburyvColchesterLeague Two · England | 0–2 | League Two · England |
| 2025-08-09 | OldhamvColchesterLeague Two · England | 1–1 | League Two · England |
| 2025-08-02 | ColchestervTranmereLeague Two · England | 1–1 | League Two · England |
| 2025-05-03 | ColchestervBarrowLeague Two · England | 0–0 | League Two · England |
| 2025-04-26 | SalfordvColchesterLeague Two · England | 4–1 | League Two · England |
| 2025-04-21 | DoncastervColchesterLeague Two · England | 3–0 | League Two · England |
| 2025-04-18 | ColchestervCreweLeague Two · England | 0–0 | League Two · England |
| 2025-04-12 | Newport CountyvColchesterLeague Two · England | 0–2 | League Two · England |
| 2025-04-05 | ColchestervNotts CountyLeague Two · England | 1–0 | League Two · England |
| 2025-04-01 | GillinghamvColchesterLeague Two · England | 1–1 | League Two · England |
| 2025-03-28 | ColchestervGrimsbyLeague Two · England | 1–2 | League Two · England |
| 2025-03-22 | BradfordvColchesterLeague Two · England | 4–1 | League Two · England |
| 2025-03-15 | ColchestervFleetwood TownLeague Two · England | 3–0 | League Two · England |
| 2025-03-11 | ColchestervPort ValeLeague Two · England | 2–1 | League Two · England |
| 2025-03-08 | CheltenhamvColchesterLeague Two · England | 0–1 | League Two · England |
| 2025-03-04 | ColchestervChesterfieldLeague Two · England | 1–0 | League Two · England |
| 2025-03-01 | Milton Keynes DonsvColchesterLeague Two · England | 0–1 | League Two · England |
| 2025-02-22 | ColchestervAFC WimbledonLeague Two · England | 1–1 | League Two · England |
| 2025-02-18 | Notts CountyvColchesterLeague Two · England | 1–1 | League Two · England |
| 2025-02-15 | CarlislevColchesterLeague Two · England | 0–0 | League Two · England |
| 2025-02-08 | ColchestervWalsallLeague Two · England | 2–1 | League Two · England |
| 2025-02-01 | TranmerevColchesterLeague Two · England | 1–3 | League Two · England |
| 2025-01-25 | ColchestervMorecambeLeague Two · England | 1–0 | League Two · England |
| 2025-01-21 | HarrogatevColchesterLeague Two · England | 0–0 | League Two · England |
| 2025-01-18 | BromleyvColchesterLeague Two · England | 0–1 | League Two · England |
| 2025-01-04 | ColchestervAccringtonLeague Two · England | 0–2 | League Two · England |
| 2025-01-01 | SwindonvColchesterLeague Two · England | 3–2 | League Two · England |