| 2022-12-29 | QPRvLutonChampionship · England | 0–3 | Championship · England |
| 2022-12-26 | LutonvNorwichChampionship · England | 2–1 | Championship · England |
| 2022-12-10 | MiddlesbroughvLutonChampionship · England | 2–1 | Championship · England |
| 2022-11-12 | LutonvRotherhamChampionship · England | 1–1 | Championship · England |
| 2022-11-08 | StokevLutonChampionship · England | 2–0 | Championship · England |
| 2022-11-05 | BlackpoolvLutonChampionship · England | 0–1 | Championship · England |
| 2022-11-01 | LutonvReadingChampionship · England | 0–0 | Championship · England |
| 2022-10-29 | LutonvSunderlandChampionship · England | 1–1 | Championship · England |
| 2022-10-23 | WatfordvLutonChampionship · England | 4–0 | Championship · England |
| 2022-10-18 | NorwichvLutonChampionship · England | 0–1 | Championship · England |
| 2022-10-15 | LutonvQPRChampionship · England | 3–1 | Championship · England |
| 2022-10-08 | West BromvLutonChampionship · England | 0–0 | Championship · England |
| 2022-10-04 | LutonvHuddersfieldChampionship · England | 3–3 | Championship · England |
| 2022-09-30 | HullvLutonChampionship · England | 0–2 | Championship · England |
| 2022-09-17 | LutonvBlackburnChampionship · England | 2–0 | Championship · England |
| 2022-09-14 | LutonvCoventryChampionship · England | 2–2 | Championship · England |
| 2022-09-03 | LutonvWiganChampionship · England | 1–2 | Championship · England |
| 2022-08-30 | CardiffvLutonChampionship · England | 1–2 | Championship · England |
| 2022-08-26 | LutonvSheffield UnitedChampionship · England | 1–1 | Championship · England |
| 2022-08-20 | SwanseavLutonChampionship · England | 0–2 | Championship · England |
| 2022-08-16 | Bristol CityvLutonChampionship · England | 2–0 | Championship · England |
| 2022-08-13 | LutonvPrestonChampionship · England | 0–1 | Championship · England |
| 2022-08-06 | BurnleyvLutonChampionship · England | 1–1 | Championship · England |
| 2022-07-30 | LutonvBirminghamChampionship · England | 0–0 | Championship · England |
| 2022-05-07 | LutonvReadingChampionship · England | 1–0 | Championship · England |
| 2022-05-02 | FulhamvLutonChampionship · England | 7–0 | Championship · England |
| 2022-04-23 | LutonvBlackpoolChampionship · England | 1–1 | Championship · England |
| 2022-04-18 | CardiffvLutonChampionship · England | 0–1 | Championship · England |
| 2022-04-15 | LutonvNott'm ForestChampionship · England | 1–0 | Championship · England |
| 2022-04-11 | HuddersfieldvLutonChampionship · England | 2–0 | Championship · England |
| 2022-04-05 | PeterborovLutonChampionship · England | 1–1 | Championship · England |
| 2022-04-02 | LutonvMillwallChampionship · England | 2–2 | Championship · England |
| 2022-03-19 | HullvLutonChampionship · England | 1–3 | Championship · England |
| 2022-03-16 | LutonvPrestonChampionship · England | 4–0 | Championship · England |
| 2022-03-13 | LutonvQPRChampionship · England | 1–2 | Championship · England |
| 2022-03-08 | CoventryvLutonChampionship · England | 0–1 | Championship · England |
| 2022-03-05 | MiddlesbroughvLutonChampionship · England | 2–1 | Championship · England |
| 2022-02-26 | LutonvDerbyChampionship · England | 1–0 | Championship · England |
| 2022-02-23 | StokevLutonChampionship · England | 1–2 | Championship · England |
| 2022-02-19 | LutonvWest BromChampionship · England | 2–0 | Championship · England |
| 2022-02-12 | BirminghamvLutonChampionship · England | 3–0 | Championship · England |
| 2022-02-08 | LutonvBarnsleyChampionship · England | 2–1 | Championship · England |
| 2022-02-01 | SwanseavLutonChampionship · England | 0–1 | Championship · England |
| 2022-01-29 | LutonvBlackburnChampionship · England | 0–0 | Championship · England |
| 2022-01-25 | LutonvBristol CityChampionship · England | 2–1 | Championship · England |
| 2022-01-22 | Sheffield UnitedvLutonChampionship · England | 2–0 | Championship · England |
| 2022-01-19 | ReadingvLutonChampionship · England | 0–2 | Championship · England |
| 2022-01-15 | LutonvBournemouthChampionship · England | 3–2 | Championship · England |