| 2022-12-31 | WolvesvMan UnitedPremier League · England | 0–1 | Premier League · England |
| 2022-12-26 | EvertonvWolvesPremier League · England | 1–2 | Premier League · England |
| 2022-11-12 | WolvesvArsenalPremier League · England | 0–2 | Premier League · England |
| 2022-11-05 | WolvesvBrightonPremier League · England | 2–3 | Premier League · England |
| 2022-10-29 | BrentfordvWolvesPremier League · England | 1–1 | Premier League · England |
| 2022-10-23 | WolvesvLeicesterPremier League · England | 0–4 | Premier League · England |
| 2022-10-18 | Crystal PalacevWolvesPremier League · England | 2–1 | Premier League · England |
| 2022-10-15 | WolvesvNott'm ForestPremier League · England | 1–0 | Premier League · England |
| 2022-10-08 | ChelseavWolvesPremier League · England | 3–0 | Premier League · England |
| 2022-10-01 | West HamvWolvesPremier League · England | 2–0 | Premier League · England |
| 2022-09-17 | WolvesvMan CityPremier League · England | 0–3 | Premier League · England |
| 2022-09-03 | WolvesvSouthamptonPremier League · England | 1–0 | Premier League · England |
| 2022-08-31 | BournemouthvWolvesPremier League · England | 0–0 | Premier League · England |
| 2022-08-28 | WolvesvNewcastlePremier League · England | 1–1 | Premier League · England |
| 2022-08-20 | TottenhamvWolvesPremier League · England | 1–0 | Premier League · England |
| 2022-08-13 | WolvesvFulhamPremier League · England | 0–0 | Premier League · England |
| 2022-08-06 | LeedsvWolvesPremier League · England | 2–1 | Premier League · England |
| 2022-05-22 | LiverpoolvWolvesPremier League · England | 3–1 | Premier League · England |
| 2022-05-15 | WolvesvNorwichPremier League · England | 1–1 | Premier League · England |
| 2022-05-11 | WolvesvMan CityPremier League · England | 1–5 | Premier League · England |
| 2022-05-07 | ChelseavWolvesPremier League · England | 2–2 | Premier League · England |
| 2022-04-30 | WolvesvBrightonPremier League · England | 0–3 | Premier League · England |
| 2022-04-24 | BurnleyvWolvesPremier League · England | 1–0 | Premier League · England |
| 2022-04-08 | NewcastlevWolvesPremier League · England | 1–0 | Premier League · England |
| 2022-04-02 | WolvesvAston VillaPremier League · England | 2–1 | Premier League · England |
| 2022-03-18 | WolvesvLeedsPremier League · England | 2–3 | Premier League · England |
| 2022-03-13 | EvertonvWolvesPremier League · England | 0–1 | Premier League · England |
| 2022-03-10 | WolvesvWatfordPremier League · England | 4–0 | Premier League · England |
| 2022-03-05 | WolvesvCrystal PalacePremier League · England | 0–2 | Premier League · England |
| 2022-02-27 | West HamvWolvesPremier League · England | 1–0 | Premier League · England |
| 2022-02-24 | ArsenalvWolvesPremier League · England | 2–1 | Premier League · England |
| 2022-02-20 | WolvesvLeicesterPremier League · England | 2–1 | Premier League · England |
| 2022-02-13 | TottenhamvWolvesPremier League · England | 0–2 | Premier League · England |
| 2022-02-10 | WolvesvArsenalPremier League · England | 0–1 | Premier League · England |
| 2022-01-22 | BrentfordvWolvesPremier League · England | 1–2 | Premier League · England |
| 2022-01-15 | WolvesvSouthamptonPremier League · England | 3–1 | Premier League · England |
| 2022-01-03 | Man UnitedvWolvesPremier League · England | 0–1 | Premier League · England |