| 2024-12-29 | Crystal PalacevSouthamptonPremier League · England | 2–1 | Premier League · England |
| 2024-12-26 | SouthamptonvWest HamPremier League · England | 0–1 | Premier League · England |
| 2024-12-22 | FulhamvSouthamptonPremier League · England | 0–0 | Premier League · England |
| 2024-12-15 | SouthamptonvTottenhamPremier League · England | 0–5 | Premier League · England |
| 2024-12-07 | Aston VillavSouthamptonPremier League · England | 1–0 | Premier League · England |
| 2024-12-04 | SouthamptonvChelseaPremier League · England | 1–5 | Premier League · England |
| 2024-11-29 | BrightonvSouthamptonPremier League · England | 1–1 | Premier League · England |
| 2024-11-24 | SouthamptonvLiverpoolPremier League · England | 2–3 | Premier League · England |
| 2024-11-09 | WolvesvSouthamptonPremier League · England | 2–0 | Premier League · England |
| 2024-11-02 | SouthamptonvEvertonPremier League · England | 1–0 | Premier League · England |
| 2024-10-26 | Man CityvSouthamptonPremier League · England | 1–0 | Premier League · England |
| 2024-10-19 | SouthamptonvLeicesterPremier League · England | 2–3 | Premier League · England |
| 2024-10-05 | ArsenalvSouthamptonPremier League · England | 3–1 | Premier League · England |
| 2024-09-30 | BournemouthvSouthamptonPremier League · England | 3–1 | Premier League · England |
| 2024-09-21 | SouthamptonvIpswichPremier League · England | 1–1 | Premier League · England |
| 2024-09-14 | SouthamptonvMan UnitedPremier League · England | 0–3 | Premier League · England |
| 2024-08-31 | BrentfordvSouthamptonPremier League · England | 3–1 | Premier League · England |
| 2024-08-24 | SouthamptonvNott'm ForestPremier League · England | 0–1 | Premier League · England |
| 2024-08-17 | NewcastlevSouthamptonPremier League · England | 1–0 | Premier League · England |