| 2021-12-16 | ChelseavEvertonPremier League · England | 1–1 | Premier League · England |
| 2021-12-12 | Crystal PalacevEvertonPremier League · England | 3–1 | Premier League · England |
| 2021-12-06 | EvertonvArsenalPremier League · England | 2–1 | Premier League · England |
| 2021-12-01 | EvertonvLiverpoolPremier League · England | 1–4 | Premier League · England |
| 2021-11-28 | BrentfordvEvertonPremier League · England | 1–0 | Premier League · England |
| 2021-11-21 | Man CityvEvertonPremier League · England | 3–0 | Premier League · England |
| 2021-11-07 | EvertonvTottenhamPremier League · England | 0–0 | Premier League · England |
| 2021-11-01 | WolvesvEvertonPremier League · England | 2–1 | Premier League · England |
| 2021-10-23 | EvertonvWatfordPremier League · England | 2–5 | Premier League · England |
| 2021-10-17 | EvertonvWest HamPremier League · England | 0–1 | Premier League · England |
| 2021-10-02 | Man UnitedvEvertonPremier League · England | 1–1 | Premier League · England |
| 2021-09-25 | EvertonvNorwichPremier League · England | 2–0 | Premier League · England |
| 2021-09-18 | Aston VillavEvertonPremier League · England | 3–0 | Premier League · England |
| 2021-09-13 | EvertonvBurnleyPremier League · England | 3–1 | Premier League · England |
| 2021-08-28 | BrightonvEvertonPremier League · England | 0–2 | Premier League · England |
| 2021-08-21 | LeedsvEvertonPremier League · England | 2–2 | Premier League · England |
| 2021-08-14 | EvertonvSouthamptonPremier League · England | 3–1 | Premier League · England |
| 2021-05-23 | Man CityvEvertonPremier League · England | 5–0 | Premier League · England |
| 2021-05-19 | EvertonvWolvesPremier League · England | 1–0 | Premier League · England |
| 2021-05-16 | EvertonvSheffield UnitedPremier League · England | 0–1 | Premier League · England |
| 2021-05-13 | Aston VillavEvertonPremier League · England | 0–0 | Premier League · England |
| 2021-05-09 | West HamvEvertonPremier League · England | 0–1 | Premier League · England |
| 2021-05-01 | EvertonvAston VillaPremier League · England | 1–2 | Premier League · England |
| 2021-04-23 | ArsenalvEvertonPremier League · England | 0–1 | Premier League · England |
| 2021-04-16 | EvertonvTottenhamPremier League · England | 2–2 | Premier League · England |
| 2021-04-12 | BrightonvEvertonPremier League · England | 0–0 | Premier League · England |
| 2021-04-05 | EvertonvCrystal PalacePremier League · England | 1–1 | Premier League · England |
| 2021-03-13 | EvertonvBurnleyPremier League · England | 1–2 | Premier League · England |
| 2021-03-08 | ChelseavEvertonPremier League · England | 2–0 | Premier League · England |
| 2021-03-04 | West BromvEvertonPremier League · England | 0–1 | Premier League · England |
| 2021-03-01 | EvertonvSouthamptonPremier League · England | 1–0 | Premier League · England |
| 2021-02-20 | LiverpoolvEvertonPremier League · England | 0–2 | Premier League · England |
| 2021-02-17 | EvertonvMan CityPremier League · England | 1–3 | Premier League · England |
| 2021-02-14 | EvertonvFulhamPremier League · England | 0–2 | Premier League · England |
| 2021-02-06 | Man UnitedvEvertonPremier League · England | 3–3 | Premier League · England |
| 2021-02-03 | LeedsvEvertonPremier League · England | 1–2 | Premier League · England |
| 2021-01-30 | EvertonvNewcastlePremier League · England | 0–2 | Premier League · England |
| 2021-01-27 | EvertonvLeicesterPremier League · England | 1–1 | Premier League · England |
| 2021-01-12 | WolvesvEvertonPremier League · England | 1–2 | Premier League · England |
| 2021-01-01 | EvertonvWest HamPremier League · England | 0–1 | Premier League · England |