| 2021-05-22 | FC KolnvSchalke 04Bundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2021-05-15 | Schalke 04vEin FrankfurtBundesliga · Germany | 4–3 | Bundesliga · Germany |
| 2021-05-12 | Schalke 04vHerthaBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2021-05-08 | HoffenheimvSchalke 04Bundesliga · Germany | 4–2 | Bundesliga · Germany |
| 2021-04-20 | BielefeldvSchalke 04Bundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2021-04-17 | FreiburgvSchalke 04Bundesliga · Germany | 4–0 | Bundesliga · Germany |
| 2021-04-11 | Schalke 04vAugsburgBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2021-04-03 | LeverkusenvSchalke 04Bundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2021-03-20 | Schalke 04vM'gladbachBundesliga · Germany | 0–3 | Bundesliga · Germany |
| 2021-03-13 | WolfsburgvSchalke 04Bundesliga · Germany | 5–0 | Bundesliga · Germany |
| 2021-03-05 | Schalke 04vMainzBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2021-02-27 | StuttgartvSchalke 04Bundesliga · Germany | 5–1 | Bundesliga · Germany |
| 2021-02-20 | Schalke 04vDortmundBundesliga · Germany | 0–4 | Bundesliga · Germany |
| 2021-02-13 | Union BerlinvSchalke 04Bundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2021-02-06 | Schalke 04vRB LeipzigBundesliga · Germany | 0–3 | Bundesliga · Germany |
| 2021-01-30 | Werder BremenvSchalke 04Bundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2021-01-24 | Schalke 04vBayern MunichBundesliga · Germany | 0–4 | Bundesliga · Germany |
| 2021-01-20 | Schalke 04vFC KolnBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2021-01-17 | Ein FrankfurtvSchalke 04Bundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2021-01-09 | Schalke 04vHoffenheimBundesliga · Germany | 4–0 | Bundesliga · Germany |
| 2021-01-02 | HerthavSchalke 04Bundesliga · Germany | 3–0 | Bundesliga · Germany |