| 2021-12-26 | OostendevGenkPro League · Belgium | 0–4 | Pro League · Belgium |
| 2021-12-18 | Beerschot VAvOostendePro League · Belgium | 0–2 | Pro League · Belgium |
| 2021-12-14 | OostendevKortrijkPro League · Belgium | 0–2 | Pro League · Belgium |
| 2021-12-10 | CharleroivOostendePro League · Belgium | 1–0 | Pro League · Belgium |
| 2021-12-04 | OostendevEupenPro League · Belgium | 2–1 | Pro League · Belgium |
| 2021-11-28 | AntwerpvOostendePro League · Belgium | 3–0 | Pro League · Belgium |
| 2021-11-21 | OostendevSt. GilloisePro League · Belgium | 1–7 | Pro League · Belgium |
| 2021-11-05 | Oud-Heverlee LeuvenvOostendePro League · Belgium | 1–0 | Pro League · Belgium |
| 2021-10-29 | OostendevMechelenPro League · Belgium | 2–4 | Pro League · Belgium |
| 2021-10-23 | KortrijkvOostendePro League · Belgium | 1–0 | Pro League · Belgium |
| 2021-10-16 | OostendevCercle BruggePro League · Belgium | 2–1 | Pro League · Belgium |
| 2021-10-02 | St TruidenvOostendePro League · Belgium | 1–1 | Pro League · Belgium |
| 2021-09-26 | OostendevAnderlechtPro League · Belgium | 2–2 | Pro League · Belgium |
| 2021-09-18 | OostendevBeerschot VAPro League · Belgium | 3–1 | Pro League · Belgium |
| 2021-09-10 | Club BruggevOostendePro League · Belgium | 3–0 | Pro League · Belgium |
| 2021-08-29 | OostendevWaregemPro League · Belgium | 0–2 | Pro League · Belgium |
| 2021-08-20 | StandardvOostendePro League · Belgium | 1–0 | Pro League · Belgium |
| 2021-08-14 | SeraingvOostendePro League · Belgium | 2–3 | Pro League · Belgium |
| 2021-08-08 | OostendevGentPro League · Belgium | 1–0 | Pro League · Belgium |
| 2021-07-30 | GenkvOostendePro League · Belgium | 3–4 | Pro League · Belgium |
| 2021-07-24 | OostendevCharleroiPro League · Belgium | 0–3 | Pro League · Belgium |
| 2021-04-18 | OostendevCercle BruggePro League · Belgium | 1–1 | Pro League · Belgium |
| 2021-04-11 | Beerschot VAvOostendePro League · Belgium | 1–2 | Pro League · Belgium |
| 2021-04-03 | OostendevWaasland-BeverenPro League · Belgium | 0–2 | Pro League · Belgium |
| 2021-03-20 | MouscronvOostendePro League · Belgium | 0–1 | Pro League · Belgium |
| 2021-03-08 | GentvOostendePro League · Belgium | 1–0 | Pro League · Belgium |
| 2021-02-27 | OostendevMechelenPro League · Belgium | 2–0 | Pro League · Belgium |
| 2021-02-20 | EupenvOostendePro League · Belgium | 1–1 | Pro League · Belgium |
| 2021-02-17 | OostendevGenkPro League · Belgium | 3–1 | Pro League · Belgium |
| 2021-02-06 | OostendevSt TruidenPro League · Belgium | 3–1 | Pro League · Belgium |
| 2021-01-31 | WaregemvOostendePro League · Belgium | 2–1 | Pro League · Belgium |
| 2021-01-28 | OostendevStandardPro League · Belgium | 2–2 | Pro League · Belgium |
| 2021-01-23 | AntwerpvOostendePro League · Belgium | 1–2 | Pro League · Belgium |
| 2021-01-20 | Club BruggevOostendePro League · Belgium | 2–1 | Pro League · Belgium |
| 2021-01-16 | OostendevKortrijkPro League · Belgium | 2–1 | Pro League · Belgium |
| 2021-01-12 | OostendevEupenPro League · Belgium | 1–1 | Pro League · Belgium |
| 2021-01-09 | OostendevCharleroiPro League · Belgium | 3–2 | Pro League · Belgium |