| 2022-01-30 | St. GilloisevAnderlechtPro League · Belgium | 1–0 | Pro League · Belgium |
| 2022-01-30 | StandardvMechelenPro League · Belgium | 1–2 | Pro League · Belgium |
| 2022-01-29 | SeraingvEupenPro League · Belgium | 0–0 | Pro League · Belgium |
| 2022-01-29 | Beerschot VAvWaregemPro League · Belgium | 3–3 | Pro League · Belgium |
| 2022-01-29 | Cercle BruggevOostendePro League · Belgium | 0–1 | Pro League · Belgium |
| 2022-01-28 | St TruidenvCharleroiPro League · Belgium | 0–1 | Pro League · Belgium |
| 2022-01-27 | Club BruggevSt. GilloisePro League · Belgium | 0–0 | Pro League · Belgium |
| 2022-01-26 | SeraingvBeerschot VAPro League · Belgium | 2–1 | Pro League · Belgium |
| 2022-01-26 | AnderlechtvCercle BruggePro League · Belgium | 0–2 | Pro League · Belgium |
| 2022-01-26 | WaregemvOud-Heverlee LeuvenPro League · Belgium | 1–1 | Pro League · Belgium |
| 2022-01-26 | EupenvStandardPro League · Belgium | 0–2 | Pro League · Belgium |
| 2022-01-25 | GentvOostendePro League · Belgium | 1–1 | Pro League · Belgium |
| 2022-01-25 | CharleroivKortrijkPro League · Belgium | 1–1 | Pro League · Belgium |
| 2022-01-25 | AntwerpvSt TruidenPro League · Belgium | 1–1 | Pro League · Belgium |
| 2022-01-23 | Cercle BruggevWaregemPro League · Belgium | 3–1 | Pro League · Belgium |
| 2022-01-23 | MechelenvAnderlechtPro League · Belgium | 0–1 | Pro League · Belgium |
| 2022-01-23 | StandardvClub BruggePro League · Belgium | 2–2 | Pro League · Belgium |
| 2022-01-23 | St. GilloisevGenkPro League · Belgium | 2–1 | Pro League · Belgium |
| 2022-01-22 | KortrijkvEupenPro League · Belgium | 1–1 | Pro League · Belgium |
| 2022-01-22 | Beerschot VAvOud-Heverlee LeuvenPro League · Belgium | 3–1 | Pro League · Belgium |
| 2022-01-22 | CharleroivGentPro League · Belgium | 0–0 | Pro League · Belgium |
| 2022-01-22 | St TruidenvSeraingPro League · Belgium | 3–1 | Pro League · Belgium |
| 2022-01-21 | OostendevAntwerpPro League · Belgium | 1–2 | Pro League · Belgium |
| 2022-01-18 | SeraingvSt. GilloisePro League · Belgium | 0–4 | Pro League · Belgium |
| 2022-01-16 | EupenvCercle BruggePro League · Belgium | 0–2 | Pro League · Belgium |
| 2022-01-16 | GenkvBeerschot VAPro League · Belgium | 4–1 | Pro League · Belgium |
| 2022-01-16 | AntwerpvCharleroiPro League · Belgium | 3–0 | Pro League · Belgium |
| 2022-01-16 | AnderlechtvStandardPro League · Belgium | 1–1 | Pro League · Belgium |
| 2022-01-15 | Oud-Heverlee LeuvenvMechelenPro League · Belgium | 5–0 | Pro League · Belgium |
| 2022-01-15 | Club BruggevSt TruidenPro League · Belgium | 2–0 | Pro League · Belgium |
| 2022-01-14 | GentvKortrijkPro League · Belgium | 2–2 | Pro League · Belgium |